PPP1R3B Antibody (C-term)

AMR09488G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
AMR09488G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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PPP1R3B Antibody (C-term)

品牌	Leading Biology	貨號	AMR09488G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPP1R3B antibody (C-term).
分子量	32695 Da
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	205-231 aa
靶點	This PPP1R3B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 205-231 amino acids from the C-terminal region of human PPP1R3B.
亞型	Rabbit Ig
通用名	PPP1R4
基因ID	79660
UniProt ID	Q86XI6
功能	Acts as a glycogen-targeting subunit for phosphatase PP1. Facilitates interaction of the PP1 with enzymes of the glycogen metabolism and regulates its activity. Suppresses the rate at which PP1 dephosphorylates (inactivates) glycogen phosphorylase and enhances the rate at which it activates glycogen synthase and therefore limits glycogen breakdown. Its activity is inhibited by PYGL, resulting in inhibition of the glycogen synthase and glycogen phosphorylase phosphatase activities of PP1. Dramatically increases basal and insulin-stimulated glycogen synthesis upon overexpression in hepatocytes (By similarity).
總結(jié)	The protein phosphatase-1 (PP1) catalytic subunit (PPP1CA;MIM 176875) is regulated by targeting subunits, such as PP1R3B.PP1R3B suppresses the rate at which PP1 dephosphorylates (i.e.,inactivates) glycogen phosphorylase (see PYGL; MIM 232700) andenhances the rate at which it activates glycogen synthase (seeGYS2; MIM 138571) (Doherty et al., 1995 [PubMed 7498521]).[suppliedby OMIM].
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Protein phosphatase 1 regulatory subunit 3B, Hepatic glycogen-targeting protein phosphatase 1 regulatory subunit GL, Protein phosphatase 1 regulatory subunit 4, PP1 subunit R4, Protein phosphatase 1 subunit GL, PTG, PPP1R3B, PPP1R4
圖像	Western blot analysis of lysate from human skeletal muscle tissue lysate, using PPP1R3B Antibody (C-term)(Cat. AMR09488G). AMR09488G was diluted at 1:1000 at each lane. A goat anti-rabbit IgG H&L(HRP) at 1:5000 dilution was used as the secondary antibody. Lysate at 35ug per lane.
說明書	Product Datasheet Protocol
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