全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM07285G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PPIL2 antibody (C-term).
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分子量 |
58823 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Note=May also localize to the cytoplasm and the cell membrane.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
402-431 aa
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靶點 |
This PPIL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 402-431 amino acids from the C-terminal region of human PPIL2.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity). May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952). May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423).
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總結(jié) |
This gene is a member of the cyclophilin family ofpeptidylprolyl isomerases. The cyclophilins are a highly conservedubiquitous family, members of which play an important role inprotein folding, immunosuppression by cyclosporin A, and infectionof HIV-1 virions. This protein interacts with the proteinaseinhibitor eglin c and is localized in the nucleus. Multipletranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Peptidyl-prolyl cis-trans isomerase-like 2, PPIase, PPIL2 (HGNC:9261)
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圖像 |
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說明書 |
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數(shù)量 |
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