全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM07618G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality RIP140 antibody (Center).
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分子量 |
126942 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus. Note=Localized to discrete foci and redistributes to larger nuclear domains upon binding to ligand- bound NR3C1
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
586-613 aa
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靶點 |
This RIP140 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 586-613 amino acids from the Central region of human RIP140.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Modulates transcriptional activation by steroid receptors such as NR3C1, NR3C2 and ESR1. Also modulates transcriptional repression by nuclear hormone receptors. Positive regulator of the circadian clock gene expression: stimulates transcription of ARNTL/BMAL1, CLOCK and CRY1 by acting as a coactivator for RORA and RORC.
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總結 |
Nuclear receptor interacting protein 1 (NRIP1) is anuclear protein that specifically interacts with thehormone-dependent activation domain AF2 of nuclear receptors. Alsoknown as RIP140, this protein modulates transcriptional activity ofthe estrogen receptor.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Nuclear receptor-interacting protein 1, Nuclear factor RIP140, Receptor-interacting protein 140, NRIP1
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圖像 |
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說明書 |
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數(shù)量 |
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