全部產品分類
品牌 |
Leading Biology | 貨號 |
AMM06461G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MPZL2 antibody (Center).
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分子量 |
24484 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
67-94 aa
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靶點 |
This MPZL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 67-94 amino acids from the Central region of human MPZL2.
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亞型 |
Rabbit Ig
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通用名 |
EVA, EVA1
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基因ID |
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UniProt ID |
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功能 |
Mediates homophilic cell-cell adhesion.
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總結 |
Thymus development depends on a complex series ofinteractions between thymocytes and the stromal component of theorgan. Epithelial V-like antigen (EVA) is expressed in thymusepithelium and strongly downregulated by thymocyte developmentalprogression. This gene is expressed in the thymus and in severalepithelial structures early in embryogenesis. It is highlyhomologous to the myelin protein zero and, in thymus-derivedepithelial cell lines, is poorly soluble in nonionic detergents,strongly suggesting an association to the cytoskeleton. Itscapacity to mediate cell adhesion through a homophilic interactionand its selective regulation by T cell maturation might imply theparticipation of EVA in the earliest phases of thymusorganogenesis. The protein bears a characteristic V-type domain andtwo potential N-glycosylation sites in the extracellular domain; aputative serine phosphorylation site for casein kinase 2 is alsopresent in the cytoplasmic tail. Two transcript variants encodingthe same protein have been found for this gene. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Myelin protein zero-like protein 2, Epithelial V-like antigen 1, MPZL2, EVA, EVA1
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圖像 |
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說明書 |
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數量 |
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