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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > PPFIBP1 Antibody (Center)

PPFIBP1 Antibody (Center)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM07269G 100 μl / ¥4950

PPFIBP1 Antibody (Center)

品牌

Leading Biology

貨號(hào)

AMM07269G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PPFIBP1 antibody (Center).

分子量

114024 Da

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

588-617 aa

靶點(diǎn)

This PPFIBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 588-617 amino acids from the Central region of human PPFIBP1.

亞型

Rabbit Ig

通用名

KIAA1230

基因ID

UniProt ID

功能

May regulate the disassembly of focal adhesions. Did not bind receptor-like tyrosine phosphatases type 2A.

總結(jié)

The protein encoded by this gene is a member of the LARprotein-tyrosine phosphatase-interacting protein (liprin) family.Liprins interact with members of LAR family of transmembraneprotein tyrosine phosphatases, which are known to be important foraxon guidance and mammary gland development. It has been proposedthat liprins are multivalent proteins that form complex structuresand act as scaffolds for the recruitment and anchoring of LARfamily of tyrosine phosphatases. This protein was found to interactwith S100A4, a calcium-binding protein related to tumorinvasiveness and metastasis. In vitro experiment demonstrated thatthe interaction inhibited the phosphorylation of this protein byprotein kinase C and protein kinase CK2. Alternatively splicedtranscript variants encoding distinct isoforms have been reported.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:2000

別名

Liprin-beta-1, Protein tyrosine phosphatase receptor type f polypeptide-interacting protein-binding protein 1, PTPRF-interacting protein-binding protein 1, hSGT2, PPFIBP1, KIAA1230

圖像

All lanes : Anti-PPFIBP1 Antibody (Center) at 1:2000 dilution Lane 1: HepG2 whole cell lysate Lane 2: Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 114 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

說(shuō)明書

數(shù)量

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