全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06099G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality KCNJ10 antibody (Center).
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分子量 |
42508 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
203-230 aa
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靶點(diǎn) |
This KCNJ10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-230 amino acids from the Central region of human KCNJ10.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
May be responsible for potassium buffering action of glial cells in the brain. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium and cesium (By similarity).
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總結(jié) |
This gene encodes a member of the inward rectifier-typepotassium channel family, characterized by having a greatertendency to allow potassium to flow into, rather than out of, acell. The encoded protein may form a heterodimer with anotherpotassium channel protein and may be responsible for the potassiumbuffering action of glial cells in the brain. Mutations in thisgene have been associated with seizure susceptibility of commonidiopathic generalized epilepsy syndromes.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
ATP-sensitive inward rectifier potassium channel 10, ATP-dependent inwardly rectifying potassium channel Kir41, Inward rectifier K(+) channel Kir12, Potassium channel, inwardly rectifying subfamily J member 10, KCNJ10
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圖像 |
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說明書 |
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數(shù)量 |
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