品牌 |
Leading Biology | 貨號 |
AMM04751G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GCNT1 antibody (Center).
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分子量 |
49799 Da
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細胞定位 |
Antigen Cellular Localization:
Golgi apparatus membrane; Single-pass type II membrane protein. Note=Also detected in the trans-Golgi network
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
63-91 aa
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靶點 |
This GCNT1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human GCNT1.
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亞型 |
Rabbit Ig
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通用名 |
NACGT2
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基因ID |
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UniProt ID |
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功能 |
Glycosyltransferase that catalyzes the transfer of an N- acetylglucosamine moiety onto mucin-type core 1 O-glycan to form the branched mucin-type core 2 O-glycan. Mucin-type core 2 O- glycans play an important role in leukocyte extravasation as they serve as scaffolds for the display of the selectin ligand sialyl Lewis X by leukocytes.
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總結 |
This gene is a member of thebeta-1,6-N-acetylglucosaminyltransferase gene family. It isessential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAcstructures and the core 2 O-glycan branch. The gene coding thisenzyme was originally mapped to 9q21, but was later localized to9q13. Multiple alternatively spliced variants, encoding the sameprotein, have been identified.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Beta-1, 3-galactosyl-O-glycosyl-glycoprotein beta-1, 6-N-acetylglucosaminyltransferase, Core 2-branching enzyme, Core2-GlcNAc-transferase, C2GNT, Core 2 GNT, GCNT1, NACGT2
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圖像 |
GCNT1 Antibody (Center) (Cat. AMM04751G) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the GCNT1 antibody detected the GCNT1 protein (arrow). |
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說明書 |
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數(shù)量 |
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