品牌 |
Leading Biology | 貨號(hào) |
APR17723G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality P4HA1 antibody (C-term).
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分子量 |
61049 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Endoplasmic reticulum lumen.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
414-442 aa
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靶點(diǎn) |
This P4HA1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 414-442 amino acids from the C-terminal region of human P4HA1.
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亞型 |
Rabbit Ig
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通用名 |
P4HA
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基因ID |
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UniProt ID |
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功能 |
Catalyzes the post-translational formation of 4- hydroxyproline in -Xaa-Pro-Gly- sequences in collagens and other proteins.
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總結(jié) |
This gene encodes a component of prolyl 4-hydroxylase, akey enzyme in collagen synthesis composed of two identical alphasubunits and two beta subunits. The encoded protein is one ofseveral different types of alpha subunits and provides the majorpart of the catalytic site of the active enzyme. In collagen andrelated proteins, prolyl 4-hydroxylase catalyzes the formation of4-hydroxyproline that is essential to the proper three-dimensionalfolding of newly synthesized procollagen chains. Alternativelyspliced transcript variants encoding different isoforms have beendescribed.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Prolyl 4-hydroxylase subunit alpha-1, 4-PH alpha-1, Procollagen-proline, 2-oxoglutarate-4-dioxygenase subunit alpha-1, P4HA1, P4HA
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圖像 |
P4HA1 Antibody (C-term) (Cat. APR17723G) western blot analysis in Ramos cell line lysates (35ug/lane).This demonstrates the P4HA1 antibody detected the P4HA1 protein (arrow). |
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說明書 |
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數(shù)量 |
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