全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號(hào) |
AMM07393G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality PTP4A1 antibody (C-term).
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分子量 |
19815 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane. Early endosome. Endoplasmic reticulum. Cytoplasm. Cytoplasm, cytoskeleton, spindle. Note=And mitotic spindle
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
140-168 aa
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靶點(diǎn) |
This PTP4A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-168 amino acids from the C-terminal region of human PTP4A1.
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亞型 |
Rabbit Ig
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通用名 |
PRL1, PTPCAAX1
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基因ID |
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UniProt ID |
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功能 |
Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.
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總結(jié) |
The protein encoded by this gene belongs to a small classof prenylated protein tyrosine phosphatases (PTPs), which containsa PTP domain and a characteristic C-terminal prenylation motif.PTPs are cell signaling molecules that play regulatory roles in avariety of cellular processes. This tyrosine phosphatase is anuclear protein, but may primarily associate with plasma membrane.The surface membrane association of this protein depends on itsC-terminal prenylation. Overexpression of this gene in mammaliancells conferred a transformed phenotype, which implicated its rolein the tumorigenesis. Studies in rat suggested that this gene maybe an immediate-early gene in mitogen-stimulated cells. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Protein tyrosine phosphatase type IVA 1, PTP(CAAXI), Protein-tyrosine phosphatase 4a1, Protein-tyrosine phosphatase of regenerating liver 1, PRL-1, PTP4A1, PRL1, PTPCAAX1
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圖像 |
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說明書 |
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數(shù)量 |
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