品牌 |
Leading Biology |
貨號(hào) |
APR08432G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MGLL antibody (N-term).
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分子量 |
33261 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
34-63 aa
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靶點(diǎn) |
This MGLL antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 34-63 amino acids from the N-terminal region of human MGLL.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Converts monoacylglycerides to free fatty acids and glycerol. Hydrolyzes the endocannabinoid 2-arachidonoylglycerol, and thereby contributes to the regulation of endocannabinoid signaling, nociperception and perception of pain (By similarity). Regulates the levels of fatty acids that serve as signaling molecules and promote cancer cell migration, invasion and tumor growth.
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總結(jié) |
Monoglyceride lipase (MGLL; EC 3.1.1.23) functionstogether with hormone-sensitive lipase (LIPE; MIM 151750) tohydrolyze intracellular triglyceride stores in adipocytes and othercells to fatty acids and glycerol. MGLL may also complementlipoprotein lipase (LPL; MIM 238600) in completing hydrolysis ofmonoglycerides resulting from degradation of lipoproteintriglycerides (Karlsson et al., 2001 [PubMed 11470505]).[suppliedby OMIM].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Monoglyceride lipase, MGL, HU-K5, Lysophospholipase homolog, Lysophospholipase-like, Monoacylglycerol lipase, MAGL, MGLL
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圖像 |
MGLL Antibody (N-term) (Cat. APR08432G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the MGLL antibody detected the MGLL protein (arrow).
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說明書 |
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數(shù)量 |
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