品牌 |
Leading Biology | 貨號 |
APR13263G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SEPT11 antibody (Center).
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分子量 |
49398 Da
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細胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Cell junction, synapse. Cell projection, dendritic spine. Cell projection, axon. Note=Partly colocalizes with stress fibers and microtubules. During bacterial infection, displays a collar shape structure next to actin at the pole of invading bacteria
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
353-382 aa
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靶點 |
This SEPT11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 353-382 amino acids from the Central region of human SEPT11.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Filament-forming cytoskeletal GTPase. May play a role in cytokinesis (Potential). May play a role in the cytoarchitecture of neurons, including dendritic arborization and dendritic spines, and in GABAergic synaptic connectivity (By similarity). During Listeria monocytogenes infection, not required for the bacterial entry process, but restricts its efficacy.
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總結(jié) |
SEPT11 belongs to the conserved septin family offilament-forming cytoskeletal GTPases that are involved in avariety of cellular functions including cytokinesis and vesicletrafficking (Hanai et al., 2004 [PubMed 15196925]; Nagata et al.,2004 [PubMed 15485874]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Septin-11, SEPT11
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圖像 |
SEPT11 Antibody (Center) (Cat. APR13263G) western blot analysis in A375 cell line lysates (35ug/lane).This demonstrates the SEPT11 antibody detected the SEPT11 protein (arrow). |
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說明書 |
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數(shù)量 |
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