品牌 |
Leading Biology | 貨號(hào) |
AMM05610G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APPBP2 antibody (Center).
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分子量 |
66853 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Nucleus. Cytoplasm, cytoskeleton. Membrane; Peripheral membrane protein Note=Associated with membranes and microtubules
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
243-271 aa
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靶點(diǎn) |
This APPBP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the Central region of human APPBP2.
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亞型 |
Rabbit Ig
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通用名 |
KIAA0228, PAT1
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基因ID |
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UniProt ID |
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功能 |
May play a role in intracellular protein transport. May be involved in the translocation of APP along microtubules toward the cell surface.
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總結(jié) |
The protein encoded by this gene interacts withmicrotubules and is functionally associated with beta-amyloidprecursor protein transport and/or processing. The beta-amyloidprecursor protein is a cell surface protein with signal-transducingproperties, and it is thought to play a role in the pathogenesis ofAlzheimer's disease. This gene has been found to be highlyexpressed in breast cancer. Multiple polyadenylation sites havebeen found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Amyloid protein-binding protein 2, Amyloid beta precursor protein-binding protein 2, APP-BP2, Protein interacting with APP tail 1, APPBP2, KIAA0228, PAT1
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圖像 |
Anti-APPBP2 Antibody (Center) at 1:1000 dilution + Jurkat whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 67 kDa Blocking/Dilution buffer: 5% NFDM/TBST. APPBP2 Antibody (Center) (Cat. AMM05610G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the APPBP2 antibody detected the APPBP2 protein (arrow). |
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說明書 |
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數(shù)量 |
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