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當(dāng)前位置:首頁(yè) > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > ACSL3 Antibody (C-term)

ACSL3 Antibody (C-term)

貨號(hào) 貨期 規(guī)格 / 價(jià)格 詢價(jià)
APG01520G 100 μl / ¥4950

ACSL3 Antibody (C-term)

品牌

Leading Biology

貨號(hào)

APG01520G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality ACSL3 antibody (C-term).

分子量

80420 Da

細(xì)胞定位

Antigen Cellular Localization: Mitochondrion outer membrane; Single-pass type III membrane protein. Peroxisome membrane; Single-pass type III membrane protein. Microsome membrane; Single-pass type III membrane protein. Endoplasmic reticulum membrane; Single-pass type III membrane protein

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

528-556 aa

靶點(diǎn)

This ACSL3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 528-556 amino acids from the C-terminal region of human ACSL3.

亞型

Rabbit Ig

通用名

ACS3, FACL3, LACS3

基因ID

UniProt ID

功能

Acyl-CoA synthetases (ACSL) activates long-chain fatty acids for both synthesis of cellular lipids, and degradation via beta-oxidation. ACSL3 mediates hepatic lipogenesis (By similarity). Preferentially uses myristate, laurate, arachidonate and eicosapentaenoate as substrates (By similarity). Has mainly an anabolic role in energy metabolism. Required for the incorporation of fatty acids into phosphatidylcholine, the major phospholipid located on the surface of VLDL (very low density lipoproteins).

總結(jié)

The protein encoded by this gene is an isozyme of thelong-chain fatty-acid-coenzyme A ligase family. Although differingin substrate specificity, subcellular localization, and tissuedistribution, all isozymes of this family convert free long-chainfatty acids into fatty acyl-CoA esters, and thereby play a key rolein lipid biosynthesis and fatty acid degradation. This isozyme ishighly expressed in brain, and preferentially utilizes myristate,arachidonate, and eicosapentaenoate as substrates. The amino acidsequence of this isozyme is 92% identical to that of rat homolog.Two transcript variants encoding the same protein have been foundfor this gene.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲(chǔ)存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

WB, E

稀釋方法

WB~~1:1000

別名

Long-chain-fatty-acid--CoA ligase 3, Long-chain acyl-CoA synthetase 3, LACS 3, ACSL3, ACS3, FACL3, LACS3

圖像

ACSL3 Antibody (C-term) (Cat. APG01520G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the ACSL3 antibody detected the ACSL3 protein (arrow).

說(shuō)明書

數(shù)量

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