全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM08244G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality TMOD1 antibody (Center).
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分子量 |
40569 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton.
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
170-198 aa
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靶點 |
This TMOD1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 170-198 amino acids from the Central region of human TMOD1.
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亞型 |
Rabbit Ig
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通用名 |
D9S57E, TMOD
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基因ID |
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UniProt ID |
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功能 |
Blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. May play an important role in regulating the organization of actin filaments by preferentially binding to a specific tropomyosin isoform at its N-terminus.
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總結(jié) |
TMOD1 is a member of the tropomodulin family. Theencoded protein is an actin-capping protein that regulatestropomyosin by binding to its N-terminus, inhibitingdepolymerization and elongation of the pointed end of actinfilaments and thereby influencing the structure of the erythrocytemembrane skeleton. Multiple transcript variants encoding the sameprotein have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Tropomodulin-1, Erythrocyte tropomodulin, E-Tmod, TMOD1, D9S57E, TMOD
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圖像 |
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說明書 |
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數(shù)量 |
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