L1CAM Antibody (C-term)

AMM06250G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMM06250G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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L1CAM Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMM06250G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality L1CAM antibody (C-term).
分子量	140003 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass type I membrane protein
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	1154-1182 aa
靶點(diǎn)	This L1CAM antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1154-1182 amino acids from the C-terminal region of human L1CAM.
亞型	Rabbit Ig
通用名	CAML1, MIC5
基因ID	3897
UniProt ID	P32004
功能	Cell adhesion molecule with an important role in the development of the nervous system. Involved in neuron-neuron adhesion, neurite fasciculation, outgrowth of neurites, etc. Binds to axonin on neurons.
總結(jié)	L1CAM is an axonal glycoproteinbelonging to the immunoglobulin supergene family. The ectodomain,consisting of several immunoglobulin-like domains andfibronectin-like repeats (type III), is linked via a singletransmembrane sequence to a conserved cytoplasmic domain. This celladhesion molecule plays an important role in nervous systemdevelopment, including neuronal migration and differentiation.Mutations in the gene cause three X-linked neurological syndromesknown by the acronym CRASH (corpus callosum hypoplasia,retardation, aphasia, spastic paraplegia and hydrocephalus).Alternative splicing of a neuron-specific exon is thought to befunctionally relevant.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Neural cell adhesion molecule L1, N-CAM-L1, NCAM-L1, CD171, L1CAM, CAML1, MIC5
圖像	Anti-L1CAM Antibody (C-term) at 1:8000 dilution + human fetal brain lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 140 kDa Blocking/Dilution buffer: 5% NFDM/TBST. L1CAM Antibody (C-term) (Cat. AMM06250G) western blot analysis in mouse cerebellum tissue lysates (35ug/lane).This demonstrates the L1CAM antibody detected the L1CAM protein (arrow).
說明書	Product Datasheet Protocol
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