品牌 |
Leading Biology | 貨號(hào) |
AMM06864G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality NUDC antibody (Center).
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分子量 |
38243 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm, cytoskeleton. Nucleus. Note=In a filamentous pattern adjacent to the nucleus of migrating cerebellar granule cells. Colocalizes with tubulin and dynein and with the microtubule organizing center. Distributed throughout the cytoplasm of non-migrating cells. A small proportion is nuclear, in a punctate pattern
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
105-133 aa
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靶點(diǎn) |
This NUDC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 105-133 amino acids from the Central region of human NUDC.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Plays a role in neurogenesis and neuronal migration (By similarity). Necessary for correct formation of mitotic spindles and chromosome separation during mitosis. Necessary for cytokinesis and cell proliferation.
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總結(jié) |
NudC was first identified as a regulator of nuclearmovement in the asexual reproductive cycle of the filamentousfungus Aspergillus nidulans. Human NUDC is a nuclear movementprotein that associates with dynein (see DYNC1H1; MIM 600112)(Aumais et al., 2003 [PubMed 12679384]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Nuclear migration protein nudC, Nuclear distribution protein C homolog, NUDC
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圖像 |
NUDC Antibody (Center) (Cat. AMM06864G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the NUDC antibody detected the NUDC protein (arrow). |
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說明書 |
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數(shù)量 |
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