品牌 |
Leading Biology |
貨號(hào) |
APR11440G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality APLP2 antibody (C-term).
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分子量 |
86956 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein. Nucleus
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
593-621 aa
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靶點(diǎn) |
This APLP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 593-621 amino acids from the C-terminal region of human APLP2.
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亞型 |
Rabbit Ig
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通用名 |
APPL2
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基因ID |
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UniProt ID |
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功能 |
May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts (By similarity).
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總結(jié) |
APLP2 may play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Amyloid-like protein 2, APLP-2, APPH, Amyloid protein homolog, CDEI box-binding protein, CDEBP, APLP2, APPL2
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圖像 |
APLP2 Antibody (C-term) (Cat. APR11440G) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the APLP2 antibody detected the APLP2 protein (arrow).
APLP2 Antibody (C-term) (Cat. APR11440G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the APLP2 antibody detected the APLP2 protein (arrow).
APLP2 Antibody (C-term) (APR11440G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of APLP2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
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說(shuō)明書(shū) |
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數(shù)量 |
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