全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR17665G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ORAI1 antibody (C-term).
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分子量 |
32668 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi- pass membrane protein Note=Isoform beta is more mobile in the plasma membrane
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
269-298 aa
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靶點 |
This ORAI1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 269-298 amino acids from the C-terminal region of human ORAI1.
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亞型 |
Rabbit Ig
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通用名 |
CRACM1, TMEM142A
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基因ID |
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UniProt ID |
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功能 |
Ca(2+) release-activated Ca(2+) (CRAC) channel subunit which mediates Ca(2+) influx following depletion of intracellular Ca(2+) stores and channel activation by the Ca(2+) sensor, STIM1. CRAC channels are the main pathway for Ca(2+) influx in T-cells and promote the immune response to pathogens by activating the transcription factor NFAT.
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總結(jié) |
CRACM1 is a plasma membrane protein essential forstore-operated calcium entry (Vig et al., 2006 [PubMed16645049]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Calcium release-activated calcium channel protein 1, Protein orai-1, Transmembrane protein 142A, ORAI1, CRACM1, TMEM142A
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圖像 |
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說明書 |
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數(shù)量 |
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