DRAGON (RGMB) Antibody (Center)

APR11799G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR11799G		100 μl / ￥4950

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DRAGON (RGMB) Antibody (Center)

品牌	Leading Biology	貨號	APR11799G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DRAGON (RGMB) antibody (Center).
分子量	47547 Da
細胞定位	Antigen Cellular Localization: Cell membrane; Lipid-anchor, GPI-anchor. Membrane raft
宿主	Rabbit
種屬反應(yīng)性	Human, Mouse
免疫原	278-309 aa
靶點	This DRAGON (RGMB) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-309 amino acids from the Central region of human DRAGON (RGMB).
亞型	Rabbit Ig
基因ID	285704
UniProt ID	Q6NW40
功能	Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
總結(jié)	Repulsive Guidance Molecule B (RGMB) is primarily expressed in the central nervous system. RGM A and B both appear at every level of the developing neural axis, where they colocalize to a large extent in the mantle layer, although only RGMA appears in the neuroepithelium, and only RGMB in the peripheral nervous system. During development, both RGMA and B appear also in lung and in limb cartilage, while RGMB has additional expression domains in pancreas.
形式	Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	RGM domain family member B, DRG11-responsive axonal guidance and outgrowth of neurite, DRAGON, RGMB
圖像	Western blot analysis of DRAGON (RGMB) Antibody (Center) in K562 cell line lysates (35ug/lane). DRAGON (arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human prostata carcinoma tissue reacted with DRAGON (RGMB) Antibody (Center) (Cat. APR11799G), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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