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BBC3 Antibody (Center)

APG02215G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APG02215G		100 μl / ￥4950

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BBC3 Antibody (Center)

品牌	Leading Biology	貨號	APG02215G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality BBC3 antibody (Center).
分子量	20532 Da
細胞定位	Antigen Cellular Localization: Mitochondrion Note=Localized to the mitochondria in order to induce cytochrome c release
宿主	Rabbit
種屬反應性	Human
免疫原	109-137 aa
靶點	This BBC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 109-137 amino acids from the Central region of human BBC3.
亞型	Rabbit Ig
通用名	PUMA
基因ID	27113
UniProt ID	Q9BXH1
功能	Essential mediator of p53/TP53-dependent and p53/TP53- independent apoptosis. Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
總結	BBC3 is an essential mediator of p53-dependent and p53-independent apoptosis.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	Bcl-2-binding component 3, JFY-1, p53 up-regulated modulator of apoptosis, BBC3, PUMA
圖像	BBC3 Antibody (Center) (Cat. APG02215G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the BBC3 antibody detected the BBC3 protein (arrow). BBC3 Antibody (Center) (Cat. APG02215G)immunohistochemistry analysis in formalin fixed and paraffin embedded human cervix tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of BBC3 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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