品牌 |
Leading Biology | 貨號 |
APR16119G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GDI2 antibody (Center).
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分子量 |
50663 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Membrane; Peripheral membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
135-164 aa
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靶點 |
This GDI2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 135-164 amino acids from the Central region of human GDI2.
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亞型 |
Rabbit Ig
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通用名 |
RABGDIB
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基因ID |
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UniProt ID |
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功能 |
Regulates the GDP/GTP exchange reaction of most Rab proteins by inhibiting the dissociation of GDP from them, and the subsequent binding of GTP to them.
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總結(jié) |
GDP dissociation inhibitors are proteins that regulate theGDP-GTP exchange reaction of members of the rab family, smallGTP-binding proteins of the ras superfamily, that are involved invesicular trafficking of molecules between cellular organelles.GDIs slow the rate of dissociation of GDP from rab proteins andrelease GDP from membrane-bound rabs. GDI2 is ubiquitouslyexpressed. The GDI2 gene contains many repetitive elementsindicating that it may be prone to inversion/deletionrearrangements. Alternative splicing results in multiple transcriptvariants encoding distinct isoforms.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Rab GDP dissociation inhibitor beta, Rab GDI beta, Guanosine diphosphate dissociation inhibitor 2, GDI-2, GDI2, RABGDIB
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圖像 |
GDI2 Antibody (Center) (Cat. APR16119G) western blot analysis in MCF-7 cell line lysates (35ug/lane).This demonstrates the GDI2 antibody detected the GDI2 protein (arrow). GDI2 Antibody (Center) (APR16119G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GDI2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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