品牌 |
Leading Biology | 貨號(hào) |
APR15392G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CDH16 antibody (C-term).
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分子量 |
89923 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type I membrane protein
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
796-824 aa
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靶點(diǎn) |
This CDH16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 796-824 amino acids from the C-terminal region of human CDH16.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Cadherins are calcium-dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types.
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總結(jié) |
This gene is a member of the cadherin superfamily, genesencoding calcium-dependent, membrane-associated glycoproteins.Mapped to a previously identified cluster of cadherin genes onchromosome 16q22.1, the gene localizes with superfamily membersCDH1, CDH3, CDH5, CDH8 and CDH11. The protein consists of anextracellular domain containing 6 cadherin domains, a transmembraneregion and a truncated cytoplasmic domain but lacks the prosequenceand tripeptide HAV adhesion recognition sequence typical of mostclassical cadherins. Expression is exclusively in kidney, where theprotein functions as the principal mediator of homotypic cellularrecognition, playing a role in the morphogenic direction of tissuedevelopment.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Cadherin-16, Kidney-specific cadherin, Ksp-cadherin, CDH16
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圖像 |
CDH16 Antibody (C-term) (Cat. APR15392G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the CDH16 antibody detected the CDH16 protein (arrow). |
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說(shuō)明書 |
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數(shù)量 |
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