全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM06947G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality DOK7 antibody (N-term).
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分子量 |
53097 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Peripheral membrane protein. Cell junction, synapse. Note=Accumulates at neuromuscular junctions
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宿主 |
Rabbit
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種屬反應性 |
Mouse
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免疫原 |
26-55 aa
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靶點 |
This DOK7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 26-55 amino acids from the N-terminal region of human DOK7.
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亞型 |
Rabbit Ig
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通用名 |
C4orf25
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基因ID |
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UniProt ID |
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功能 |
Probable muscle-intrinsic activator of MUSK that plays an essential role in neuromuscular synaptogenesis. Acts in aneural activation of MUSK and subsequent acetylcholine receptor (AchR) clustering in myotubes. Induces autophosphorylation of MUSK.
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總結 |
The protein encoded by this gene is essential forneuromuscular synaptogenesis. The protein functions in aneuralactivation of muscle-specific receptor kinase, which is requiredfor postsynaptic differentiation, and in the subsequent clusteringof the acetylcholine receptor in myotubes. This protein can alsoinduce autophosphorylation of muscle-specific receptor kinase.Mutations in this gene are a cause of familial limb-girdlemyasthenia autosomal recessive, which is also known as congenitalmyasthenic syndrome type 1B. Alternative splicing results inmultiple transcript variants.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Protein Dok-7, Downstream of tyrosine kinase 7, DOK7, C4orf25
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圖像 |
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說明書 |
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數(shù)量 |
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