IMPDH1 Antibody (C-term)

APR07996G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR07996G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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IMPDH1 Antibody (C-term)

品牌	Leading Biology	貨號	APR07996G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality IMPDH1 antibody (C-term).
分子量	55406 Da
細胞定位	Antigen Cellular Localization: Cytoplasm {ECO:0000255\|HAMAP-Rule:MF_03156, ECO:0000269\|PubMed:14766016}. Nucleus {ECO:0000255\|HAMAP- Rule:MF_03156, ECO:0000269\|PubMed:14766016}
宿主	Rabbit
種屬反應性	Human
免疫原	487-514 aa
靶點	This IMPDH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 487-514 amino acids from the C-terminal region of human IMPDH1.
亞型	Rabbit Ig
通用名	IMPD1
基因ID	3614
UniProt ID	P20839
功能	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate- limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.
總結	The protein encoded by this gene acts as a homotetramer to regulate cell growth. The encoded protein is an enzyme that catalyzes the synthesis of xanthine monophosphate (XMP) from inosine-5'-monophosphate (IMP). This is the rate-limiting step in the de novo synthesis of guanine nucleotides. Defects in this gene are a cause of retinitis pigmentosa type 10 (RP10). Several transcript variants encoding different isoforms have been found for this gene.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, IF, IHC-P, E
稀釋方法	WB~~1:1000 IF~~1:10~50 IHC-P~~1:10~50
別名	Inosine-5'-monophosphate dehydrogenase 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMP dehydrogenase 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH 1 {ECO:0000255\|HAMAP-Rule:MF_03156}, 111205 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPDH-I, IMPDH1 {ECO:0000255\|HAMAP-Rule:MF_03156}, IMPD1
圖像	IMPDH1 Antibody (C-term) (Cat. APR07996G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the IMPDH1 antibody detected the IMPDH1 protein (arrow). Confocal immunofluorescent analysis of IMPDH1 Antibody (C-term) ( APR07996G) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue). IMPDH1 Antibody (C-term) (APR07996G)immunohistochemistry analysis in formalin fixed and paraffin embedded human breast carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of IMPDH1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說明書	Product Datasheet Protocol
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