品牌 |
Leading Biology | 貨號(hào) |
APR10251G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality SSX4 antibody (Center).
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分子量 |
21858 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
63-91 aa
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靶點(diǎn) |
This SSX4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-91 amino acids from the Central region of human SSX4.
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亞型 |
Rabbit Ig
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通用名 |
SSX4A
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基因ID |
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UniProt ID |
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功能 |
Could act as a modulator of transcription.
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總結(jié) |
The product of this gene belongs to the family of highlyhomologous synovial sarcoma X (SSX) breakpoint proteins. Theseproteins may function as transcriptional repressors. They are alsocapable of eliciting spontaneously humoral and cellular immuneresponses in cancer patients, and are potentially useful targets incancer vaccine-based immunotherapy. SSX1, SSX2 and SSX4 genes havebeen involved in the t(X;18) translocation characteristically foundin all synovial sarcomas. This translocation results in the fusionof the synovial sarcoma translocation gene on chromosome 18 to oneof the SSX genes on chromosome X. Chromosome Xp11 contains asegmental duplication resulting in two identical copies of synovialsarcoma, X breakpoint 4, SSX4 and SSX4B, in tail-to-tailorientation. This gene, SSX4B, represents the more centromericcopy. Two transcript variants encoding distinct isoforms have beenidentified for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Protein SSX4, Cancer/testis antigen 54, CT54, SSX4, SSX4A
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圖像 |
SSX4 Antibody (Center) (Cat. APR10251G) western blot analysis in CEM,K562,NCI-H292,MDA-MB453,A549 cell line lysates (35ug/lane).This demonstrates the SSX4 antibody detected the SSX4 protein (arrow). |
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說明書 |
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數(shù)量 |
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