MRAP2 Antibody (Center)

AMM06462G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
AMM06462G		100 μl / ￥4950

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MRAP2 Antibody (Center)

品牌	Leading Biology	貨號(hào)	AMM06462G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality MRAP2 antibody (Center).
分子量	23548 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Single-pass membrane protein Endoplasmic reticulum membrane; Single-pass membrane protein Note=The formation of antiparallel homo- and heterodimers suggest that N- and C-terminus can both localize in the cytoplasmic and extracellular parts, depending on the context
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	58-86 aa
靶點(diǎn)	This MRAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 58-86 amino acids from the Central region of human MRAP2.
亞型	Rabbit Ig
通用名	C6orf117
基因ID	112609
UniProt ID	Q96G30
功能	Modulator of melanocortin receptor 4 (MC4R), a receptor involved in energy homeostasis. Plays a central role in the control of energy homeostasis and body weight regulation by increasing ligand-sensitivity of MC4R and MC4R-mediated generation of cAMP (By similarity). May also act as a negative regulator of MC2R: competes with MRAP for binding to MC2R and impairs the binding of corticotropin (ACTH) to MC2R. May also regulate activity of other melanocortin receptors (MC1R, MC3R and MC5R); however, additional evidences are required in vivo.
總結(jié)	The specific function of this protein remains unknown.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50
別名	Melanocortin-2 receptor accessory protein 2, MC2R accessory protein 2, MRAP2, C6orf117
圖像	MRAP2 Antibody (Center) (Cat. AMM06462G) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the MRAP2 antibody detected the MRAP2 protein (arrow). MRAP2 Antibody (Center) (Cat. AMM06462G)immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MRAP2 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
說(shuō)明書(shū)	Product Datasheet Protocol
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