品牌 |
Leading Biology | 貨號 |
APR11528G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CACNG4 antibody (Center).
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分子量 |
36579 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
147-175 aa
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靶點 |
This CACNG4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 147-175 amino acids from the Central region of human CACNG4.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Regulates the trafficking and gating properties of AMPA- selective glutamate receptors (AMPARs). Promotes their targeting to the cell membrane and synapses and modulates their gating properties by slowing their rates of activation, deactivation and desensitization and by mediating their resensitization. Does not show subunit-specific AMPA receptor regulation and regulates all AMPAR subunits. Thought to stabilize the calcium channel in an inactivated (closed) state.
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總結(jié) |
The protein encoded by this gene is a type I transmembraneAMPA receptor regulatory protein (TARP). TARPs regulate bothtrafficking and channel gating of the AMPA receptors. This gene ispart of a functionally diverse eight-member protein subfamily ofthe PMP-22/EMP/MP20 family and is located in a cluster with twofamily members, a type II TARP and a calcium channel gamma subunit.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Voltage-dependent calcium channel gamma-4 subunit, Neuronal voltage-gated calcium channel gamma-4 subunit, Transmembrane AMPAR regulatory protein gamma-4, TARP gamma-4, CACNG4
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圖像 |
CACNG4 Antibody (Center) (Cat. APR11528G) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the CACNG4 antibody detected the CACNG4 protein (arrow). CACNG4 Antibody (Center) (Cat. APR11528G) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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