全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR07074G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ATP1B3 antibody (C-term).
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分子量 |
31513 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cell membrane; Single-pass type II membrane protein. Melanosome. Note=Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
241-270 aa
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靶點(diǎn) |
This ATP1B3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 241-270 amino acids from the C-terminal region of human ATP1B3.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
This is the non-catalytic component of the active enzyme, which catalyzes the hydrolysis of ATP coupled with the exchange of Na(+) and K(+) ions across the plasma membrane. The exact function of the beta-3 subunit is not known.
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總結(jié) |
The protein encoded by this gene belongs to the family ofNa+/K+ and H+/K+ ATPases beta chain proteins, and to the subfamilyof Na+/K+ -ATPases. Na+/K+ -ATPase is an integral membrane proteinresponsible for establishing and maintaining the electrochemicalgradients of Na and K ions across the plasma membrane. Thesegradients are essential for osmoregulation, for sodium-coupledtransport of a variety of organic and inorganic molecules, and forelectrical excitability of nerve and muscle. This enzyme iscomposed of two subunits, a large catalytic subunit (alpha) and asmaller glycoprotein subunit (beta). The beta subunit regulates,through assembly of alpha/beta heterodimers, the number of sodiumpumps transported to the plasma membrane. The glycoprotein subunitof Na+/K+ -ATPase is encoded by multiple genes. This gene encodes abeta 3 subunit. This gene encodes a beta 3 subunit. A pseudogeneexists for this gene, and it is located on chromosome 2. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
Sodium/potassium-transporting ATPase subunit beta-3, Sodium/potassium-dependent ATPase subunit beta-3, ATPB-3, CD298, ATP1B3
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圖像 |
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說明書 |
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數(shù)量 |
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