品牌 |
Leading Biology |
貨號 |
APR16648G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GTPBP10 antibody (C-term).
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分子量 |
42933 Da
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細胞定位 |
Antigen Cellular Localization:
Nucleus, nucleolus. Chromosome. Note=Found in the dense fibrillar compartment region of the nucleolus. At the onset of mitosis moves to the chromosome surface and remains there until anaphase Gradually re-assembles into the nucleolus at late anaphase to telophase
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
243-271 aa
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靶點 |
This GTPBP10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 243-271 amino acids from the C-terminal region of human GTPBP10.
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亞型 |
Rabbit Ig
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通用名 |
OBGH2
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基因ID |
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UniProt ID |
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功能 |
May be involved in the ribosome maturation process. Complements an ObgE(CgtA) function in E.coli ribosome maturation. Plays a role of GTPase in vitro. When missing, disorganization of the nuceleolar architecture is observed.
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總結(jié) |
Small G proteins, such as GTPBP10, act as molecularswitches that play crucial roles in the regulation of fundamentalcellular processes such as protein synthesis, nuclear transport,membrane trafficking, and signal transduction (Hirano et al., 2006[PubMed 17054726]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
GTP-binding protein 10, Protein obg homolog 2, ObgH2, GTPBP10, OBGH2
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圖像 |
Anti-GTPBP10 Antibody (C-term) at 1:1000 dilution + A549 whole cell lysate
Lysates/proteins at 20 μg per lane.
Secondary
Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution.
Predicted band size : 43 kDa
Blocking/Dilution buffer: 5% NFDM/TBST.
GTPBP10 Antibody (C-term) (Cat. APR16648G) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the GTPBP10 antibody detected the GTPBP10 protein (arrow).
GTPBP10 Antibody (C-term) (Cat. APR16648G) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the GTPBP10 antibody detected the GTPBP10 protein (arrow).
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說明書 |
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數(shù)量 |
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