品牌 |
Leading Biology | 貨號 |
APR17286G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality MAP3K15 antibody (N-term).
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分子量 |
147437 Da
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human, Mouse
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免疫原 |
315-342 aa
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靶點(diǎn) |
This MAP3K15 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 315-342 amino acids from the N-terminal region of human MAP3K15.
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亞型 |
Rabbit Ig
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通用名 |
ASK3
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基因ID |
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UniProt ID |
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功能 |
May function in a signal transduction pathway that is activated by various cell stresses and leads to apoptosis.
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總結(jié) |
The protein encoded by this gene is a member of themitogen-activated protein kinase (MAPK) family. These familymembers function in a protein kinase signal transduction cascade,where an activated MAPK kinase kinase (MAP3K) phosphorylates andactivates a specific MAPK kinase (MAP2K), which then activates aspecific MAPK. This MAP3K protein plays an essential role inapoptotic cell death triggered by cellular stresses. [provided byRefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
FC~~1:10~50
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別名 |
Mitogen-activated protein kinase kinase kinase 15, Apoptosis signal-regulating kinase 3, MAPK/ERK kinase kinase 15, MEK kinase 15, MEKK 15, MAP3K15, ASK3
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圖像 |
Anti-MAP3K15 Antibody (N-term) at 1:1000 dilution + human fetal brain lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 147 kDa Blocking/Dilution buffer: 5% NFDM/TBST. MAP3K15 Antibody (N-term) (Cat. APR17286G) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the MAP3K15 antibody detected the MAP3K15 protein (arrow). MAP3K15 Antibody (N-term) (Cat. APR17286G)immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of MAP3K15 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. |
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說明書 |
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數(shù)量 |
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