全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
AMM05300G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HAX1 antibody (C-term).
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分子量 |
31621 Da
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細胞定位 |
Antigen Cellular Localization:
Mitochondrion. Endoplasmic reticulum. Nucleus membrane. Cytoplasmic vesicle. Sarcoplasmic reticulum
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
161-190 aa
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靶點 |
This HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 161-190 amino acids from the C-terminal region of human HAX1.
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亞型 |
Rabbit Ig
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通用名 |
HS1BP1
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基因ID |
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UniProt ID |
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功能 |
Promotes cell survival. Potentiates GNA13-mediated cell migration. Involved in the clathrin-mediated endocytosis pathway. May be involved in internalization of ABC transporters such as ABCB11. May inhibit CASP9 and CASP3. May regulate intracellular calcium pools.
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總結(jié) |
The protein encoded by this gene is known to associatewith hematopoietic cell-specific Lyn substrate 1, a substrate ofSrc family tyrosine kinases. It also interacts with the product ofthe polycystic kidney disease 2 gene, mutations in which areassociated with autosomal-dominant polycystic kidney disease, andwith the F-actin-binding protein, cortactin. It was earlier thoughtthat this gene product is mainly localized in the mitochondria,however, recent studies indicate it to be localized in the cellbody. Mutations in this gene result in autosomal recessive severecongenital neutropenia, also known as Kostmann disease. Twotranscript variants encoding different isoforms have been found forthis gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:10~50
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別名 |
HCLS1-associated protein X-1, HS1-associating protein X-1, HAX-1, HS1-binding protein 1, HSP1BP-1, HAX1, HS1BP1
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圖像 |
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說明書 |
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數(shù)量 |
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