RHEB Antibody (C-term)

AMR09752G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
AMR09752G		100 μl / ￥4950

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安諾倫（北京）生物科技有限公司

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RHEB Antibody (C-term)

品牌	Leading Biology	貨號(hào)	AMR09752G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RHEB antibody (C-term).
分子量	20497 Da
細(xì)胞定位	Antigen Cellular Localization: Endomembrane system {ECO:0000269\|PubMed:22002721, ECO:0000305}; Lipid-anchor {ECO:0000269\|PubMed:22002721, ECO:0000305}; Cytoplasmic side {ECO:0000269\|PubMed:15489334, ECO:0000305}. Golgi apparatus membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytosol. Endoplasmic reticulum membrane; Lipid-anchor; Cytoplasmic side
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	104-134 aa
靶點(diǎn)	This RHEB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 104-134 amino acids from the C-terminal region of human RHEB.
亞型	Rabbit Ig
通用名	RHEB2
基因ID	6009
UniProt ID	Q15382
功能	Activates the protein kinase activity of mTORC1, and thereby plays a role in the regulation of apoptosis. Stimulates the phosphorylation of S6K1 and EIF4EBP1 through activation of mTORC1 signaling. Has low intrinsic GTPase activity.
總結(jié)	This gene is a member of the small GTPase superfamily andencodes a lipid-anchored, cell membrane protein with five repeatsof the RAS-related GTP-binding region. This protein is vital inregulation of growth and cell cycle progression due to its role inthe insulin/TOR/S6K signaling pathway. The protein has GTPaseactivity and shuttles between a GDP-bound form and a GTP-boundform, and farnesylation of the protein is required for thisactivity. Three pseudogenes have been mapped, two on chromosome 10and one on chromosome 22.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100
別名	GTP-binding protein Rheb, Ras homolog enriched in brain, RHEB, RHEB2
圖像	RHEB Antibody (C-term) (Cat. AMR09752G) western blot analysis in MDA-MB231 cell line lysates (35ug/lane).This demonstrates the RHEB antibody detected the RHEB protein (arrow). RHEB Antibody (C-term) (Cat. AMR09752G)immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of RHEB Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
說(shuō)明書	Product Datasheet Protocol
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