全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APG02754G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CPT1C antibody (C-term).
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分子量 |
90989 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Mitochondrion outer membrane; Multi-pass membrane protein. Cell junction, synapse
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
752-782 aa
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靶點 |
This CPT1C antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 752-782 amino acids from the C-terminal region of human CPT1C.
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亞型 |
Rabbit Ig
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通用名 |
CATL1
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基因ID |
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UniProt ID |
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總結(jié) |
The Cpt1 family of proteins are outer mitochondrial membrane proteins that regulate the entry into, and oxidation of fatty acids by, mitochondria. Malonyl-CoA, an intermediate in fatty acid synthesis, has been implicated as a regulatory component of the energy sensing system that feeds into hypothalmic neurons to impart energy homeostasis. Malonyl-CoA levels in the hypothalamus are dynamically regulated by fasting and feeding, altering subsequent feeding behaviour. Cpt1c, the brain-specific carnitine O-palmitoyltransferase 1, is thought to relay information about malonyl-CoA levels in hypothalamic neurons that express orexigenic and anorexigenic neuropeptides that regulate food intake and peripheral energy expenditure. Unlike other Cpt1 proteins, Cpt1c binds Malonyl-CoA but does not catalyse the transfer of the malonyl group from CoA to carnitine.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, FC, E
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稀釋方法 |
WB~~1:1000
FC~~1:10~50
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別名 |
Carnitine O-palmitoyltransferase 1, brain isoform, CPT1-B, CPT IC, Carnitine O-palmitoyltransferase I, brain isoform, CPTI-B, Carnitine palmitoyltransferase 1C, CPT1C, CATL1
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圖像 |
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說明書 |
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數(shù)量 |
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