品牌 |
Leading Biology | 貨號 |
APR12271G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GRIN2A antibody (C-term).
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分子量 |
165283 Da
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細胞定位 |
Antigen Cellular Localization:
Cell membrane; Multi-pass membrane protein. Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
1291-1318 aa
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靶點 |
This GRIN2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1291-1318 amino acids from the C-terminal region of human GRIN2A.
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亞型 |
Rabbit Ig
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通用名 |
NMDAR2A
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基因ID |
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UniProt ID |
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功能 |
NMDA receptor subtype of glutamate-gated ion channels possesses high calcium permeability and voltage-dependent sensitivity to magnesium. Activation requires binding of agonist to both types of subunits.
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總結 |
N-methyl-D-aspartate (NMDA) receptors are a class ofionotropic glutamate-gated ion channels. These receptors have beenshown to be involved in long-term potentiation, anactivity-dependent increase in the efficiency of synaptictransmission thought to underlie certain kinds of memory andlearning. NMDA receptor channels are heteromers composed of the keyreceptor subunit NMDAR1 (GRIN1) and 1 or more of the 4 NMDAR2subunits: NMDAR2A (GRIN2A), NMDAR2B (GRIN2B), NMDAR2C (GRIN2C) andNMDAR2D (GRIN2D). Alternatively spliced transcript variantsencoding different isoforms have been found for this gene.
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Glutamate receptor ionotropic, NMDA 2A, GluN2A, Glutamate [NMDA] receptor subunit epsilon-1, N-methyl D-aspartate receptor subtype 2A, NMDAR2A, NR2A, hNR2A, GRIN2A, NMDAR2A
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圖像 |
Anti-GRIN2A Antibody (C-term) at 1:1000 dilution + MDA-MB-453 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 165 kDa Blocking/Dilution buffer: 5% NFDM/TBST. GRIN2A Antibody (C-term) (Cat. APR12271G)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GRIN2A Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. GRIN2A Antibody (C-term) (Cat. APR12271G) flow cytometric analysis of MDA-MB435 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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