品牌 |
Leading Biology | 貨號(hào) |
AMM04763G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality GGH antibody (N-term).
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分子量 |
35964 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Secreted, extracellular space. Lysosome. Melanosome. Note=While its intracellular location is primarily the lysosome, most of the enzyme activity is secreted. Identified by mass spectrometry in melanosome fractions from stage I to stage IV
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宿主 |
Rabbit
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種屬反應(yīng)性 |
Human
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免疫原 |
7-34 aa
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靶點(diǎn) |
This GGH antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 amino acids from the N-terminal region of human GGH.
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亞型 |
Rabbit Ig
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基因ID |
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UniProt ID |
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功能 |
Hydrolyzes the polyglutamate sidechains of pteroylpolyglutamates. Progressively removes gamma-glutamyl residues from pteroylpoly-gamma-glutamate to yield pteroyl-alpha- glutamate (folic acid) and free glutamate. May play an important role in the bioavailability of dietary pteroylpolyglutamates and in the metabolism of pteroylpolyglutamates and antifolates.
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總結(jié) |
This gene catalyzes the hydrolysis offolylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates bythe removal of gamma-linked polyglutamates and glutamate. [providedby RefSeq].
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
WB, IHC-P, FC, E
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稀釋方法 |
WB~~1:1000
IHC-P~~1:50~100
FC~~1:10~50
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別名 |
Gamma-glutamyl hydrolase, Conjugase, GH, Gamma-Glu-X carboxypeptidase, GGH
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圖像 |
GGH Antibody (N-term) (Cat. AMM04763G) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the GGH antibody detected the GGH protein (arrow). GGH Antibody (N-term) (Cat. AMM04763G)immunohistochemistry analysis in formalin fixed and paraffin embedded human liver tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GGH Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. GGH Antibody (N-term) (Cat. AMM04763G) flow cytometric analysis of HL-60 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. |
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說明書 |
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數(shù)量 |
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