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當(dāng)前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > SAR1B Antibody (Center)

SAR1B Antibody (Center)

貨號 貨期 規(guī)格 / 價(jià)格 詢價(jià)
AMM07712G 100 μl / ¥4950

SAR1B Antibody (Center)

品牌

Leading Biology

貨號

AMM07712G

產(chǎn)品分類

Polyclonal Antibodies

研究領(lǐng)域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality SAR1B antibody (Center).

分子量

22410 Da

細(xì)胞定位

Antigen Cellular Localization: Endoplasmic reticulum membrane; Peripheral membrane protein. Golgi apparatus, Golgi stack membrane; Peripheral membrane protein. Note=Associated with the endoplasmic reticulum and Golgi stacks, in particular in the juxta-nuclear Golgi region.

宿主

Rabbit

種屬反應(yīng)性

Human

免疫原

89-116 aa

靶點(diǎn)

This SAR1B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 89-116 amino acids from the Central region of human SAR1B.

亞型

Rabbit Ig

通用名

SARA2, SARB

基因ID

UniProt ID

功能

Involved in transport from the endoplasmic reticulum to the Golgi apparatus. Activated by the guanine nucleotide exchange factor PREB. Involved in the selection of the protein cargo and the assembly of the COPII coat complex.

總結(jié)

The protein encoded by this gene is a small GTPase thatacts as a homodimer. The encoded protein is activated by theguanine nucleotide exchange factor PREB and is involved in proteintransport from the endoplasmic reticulum to the Golgi. This proteinis part of the COPII coat complex. Defects in this gene are a causeof chylomicron retention disease (CMRD), also known as Andersondisease (ANDD). Two transcript variants encoding the same proteinhave been found for this gene.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應(yīng)用

IHC-P, WB, FC, E

稀釋方法

IHC-P~~1:50~100 WB~~1:1000 FC~~1:10~50

別名

GTP-binding protein SAR1b, GTP-binding protein B, GTBPB, SAR1B, SARA2, SARB

圖像

SAR1B antibody (Center) (Cat. AMM07712G) immunohistochemistry analysis in formalin fixed and paraffin embedded human skeletal muscle followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the SAR1B antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.

SAR1B Antibody (Center) (Cat. AMM07712G) western blot analysis in MCF-7,MDA-MB453 cell line lysates (35ug/lane).This demonstrates the SAR1B antibody detected the SAR1B protein (arrow).

SAR1B Antibody (Center) (Cat. AMM07712G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

說明書

數(shù)量

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