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TIAM2 Antibody (internal region)

貨號 貨期 規(guī)格 / 價格 詢價
AMM08203G 0.1 mg / ¥4950

TIAM2 Antibody (internal region)

品牌

Leading Biology

貨號

AMM08203G

產品分類

Polyclonal Antibodies

研究領域

產品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality TIAM2 antibody (internal region).

分子量

190103 Da

細胞定位

Antigen Cellular Localization: Cytoplasm. Cell projection, lamellipodium. Cell projection, filopodium. Cell projection, growth cone. Note=Localizes to the plasma membrane in neurites.

宿主

Goat

亞型

IgG

通用名

KIAA2016, STEF

基因ID

UniProt ID

功能

Modulates the activity of RHO-like proteins and connects extracellular signals to cytoskeletal activities. Acts as a GDP- dissociation stimulator protein that stimulates the GDP-GTP exchange activity of RHO-like GTPases and activates them. Mediates extracellular laminin signals to activate Rac1, contributing to neurite growth. Involved in lamellipodial formation and advancement of the growth cone of embryonic hippocampal neurons. Promotes migration of neurons in the cerebral cortex. When overexpressed, induces membrane ruffling accompanied by the accumulation of actin filaments along the altered plasma membrane (By similarity). Activates specifically RAC1, but not CDC42 and RHOA.

總結

This antibody is expected to recognize all reported isoforms (NP_036586.2; NP_001010927.1).

形式

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

E

別名

T-lymphoma invasion and metastasis-inducing protein 2, TIAM-2, SIF and TIAM1-like exchange factor, TIAM2, KIAA2016, STEF

說明書

數(shù)量

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