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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > DTX1 / Deltex-1 Antibody (internal region, near N-Term)

DTX1 / Deltex-1 Antibody (internal region, near N-Term)

貨號 貨期 規(guī)格 / 價格 詢價
AMM05847G 0.1 mg / ¥4950

DTX1 / Deltex-1 Antibody (internal region, near N-Term)

品牌

Leading Biology

貨號

AMM05847G

產(chǎn)品分類

Polyclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DTX1 / Deltex-1 antibody (internal region, near N-Term).

分子量

67368 Da

細胞定位

Antigen Cellular Localization: Cytoplasm. Nucleus. Note=Predominantly cytoplasmic. Associates with endocytic vesicles. Partially nuclear

宿主

Goat

亞型

IgG

基因ID

UniProt ID

功能

Functions as a ubiquitin ligase protein in vivo, mediating ubiquitination and promoting degradation of MEKK1, suggesting that it may regulate the Notch pathway via some ubiquitin ligase activity (By similarity). Regulator of Notch signaling, a signaling pathway involved in cell-cell communications that regulates a broad spectrum of cell-fate determinations. Mainly acts as a positive regulator of Notch, but it also acts as a negative regulator, depending on the developmental and cell context. Mediates the antineural activity of Notch, possibly by inhibiting the transcriptional activation mediated by MATCH1. Involved in neurogenesis, lymphogenesis and myogenesis, and may also be involved in MZB (Marginal zone B) cell differentiation. Promotes B-cell development at the expense of T- cell development, suggesting that it can antagonize NOTCH1.

形式

0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

E

別名

E3 ubiquitin-protein ligase DTX1, 6.3.2.-, Protein deltex-1, Deltex1, hDTX1, DTX1

說明書

數(shù)量

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