全部產(chǎn)品分類
品牌 |
Leading Biology | 貨號 |
APR15218G |
產(chǎn)品分類 |
Polyclonal Antibodies | 研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality CACNA1G antibody (internal region).
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分子量 |
262472 Da
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細胞定位 |
Antigen Cellular Localization:
Membrane; Multi-pass membrane protein.
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宿主 |
Goat
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亞型 |
IgG
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通用名 |
KIAA1123
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基因ID |
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UniProt ID |
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功能 |
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1G gives rise to T-type calcium currents. T-type calcium channels belong to the "low-voltage activated (LVA)" group and are strongly blocked by mibefradil. A particularity of this type of channel is an opening at quite negative potentials and a voltage-dependent inactivation. T-type channels serve pacemaking functions in both central neurons and cardiac nodal cells and support calcium signaling in secretory cells and vascular smooth muscle. They may also be involved in the modulation of firing patterns of neurons which is important for information processing as well as in cell growth processes.
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總結(jié) |
This antibody is expected to recognize isoform 1 (NP_061496.2), 4 (NP_938199.1), 5 (NP_938194.1), 8 (NP_938198.1), 9 (NP_938192.1), 10 (NP_938200.1) and isoform 15 (NP_938407.1).
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
E
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別名 |
Voltage-dependent T-type calcium channel subunit alpha-1G, Cav3.1c, NBR13, Voltage-gated calcium channel subunit alpha Cav3.1, CACNA1G, KIAA1123
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說明書 |
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數(shù)量 |
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