品牌 |
Leading Biology |
貨號(hào) |
APG01430G |
產(chǎn)品分類 |
Polyclonal Antibodies |
研究領(lǐng)域 |
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產(chǎn)品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality ABCE1 / RNase L antibody (N-Term).
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分子量 |
67314 Da
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細(xì)胞定位 |
Antigen Cellular Localization:
Cytoplasm. Mitochondrion. Note=Localized to clusters of virus formation at the plasma membrane
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宿主 |
Goat
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亞型 |
IgG
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通用名 |
RLI, RNASEL1, RNASELI, RNS4I
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基因ID |
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UniProt ID |
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功能 |
Antagonizes the binding of 2-5A (5'-phosphorylated 2',5'-linked oligoadenylates) by RNase L through direct interaction with RNase L and therefore inhibits its endoribonuclease activity. May play a central role in the regulation of mRNA turnover. Antagonizes the anti-viral effect of the interferon-regulated 2-5A/RNase L pathway. May act as a chaperone for post-translational events during HIV-1 capsid assembly.
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總結(jié) |
Reported variants represent identical protein: NP_002931.2 NP_001035809.1
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形式 |
0.5 mg/ml in Tris saline, 0.02% sodium azide, pH7.3 with 0.5% bovine serum albumin
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儲(chǔ)存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應(yīng)用 |
E
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別名 |
ATP-binding cassette sub-family E member 1, 2'-5'-oligoadenylate-binding protein, HuHP68, RNase L inhibitor, Ribonuclease 4 inhibitor, RNS4I, ABCE1, RLI, RNASEL1, RNASELI, RNS4I
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說(shuō)明書 |
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數(shù)量 |
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