RAB3GAP2 Antibody (C-term)

APR14073G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR14073G		100 μl / ￥5450

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RAB3GAP2 Antibody (C-term)

品牌	Leading Biology	貨號(hào)	APR14073G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality RAB3GAP2 antibody (C-term).
分子量	155985 Da
細(xì)胞定位	Antigen Cellular Localization: Cytoplasm. Note=In neurons, it is enriched in the synaptic soluble fraction
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	943-972 aa
靶點(diǎn)	This RAB3GAP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 943-972 amino acids from the C-terminal region of human RAB3GAP2.
亞型	Rabbit Ig
通用名	KIAA0839
基因ID	25782
UniProt ID	Q9H2M9
功能	Regulatory subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Rab3 GTPase-activating complex specifically converts active Rab3-GTP to the inactive form Rab3- GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non- synaptic vesicular release of neurotransmitters.
總結(jié)	RAB3GAP2 belongs to the RAB3 protein family, members of which are involved in regulated exocytosis of neurotransmitters and hormones. This protein forms the Rab3 GTPase-activating complex with RAB3GAP1, where it constitutes the regulatory subunit, whereas the latter functions as the catalytic subunit. This gene has the highest level of expression in the brain, consistent with it having a key role in neurodevelopment.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	Rab3 GTPase-activating protein non-catalytic subunit, RGAP-iso, Rab3 GTPase-activating protein 150 kDa subunit, Rab3-GAP p150, Rab3-GAP150, Rab3-GAP regulatory subunit, RAB3GAP2, KIAA0839
圖像	Western blot analysis of RAB3GAP2 Antibody (C-term) (Cat. APR14073G) in HL-60 cell line lysates (35ug/lane). RAB3GAP2 (arrow) was detected using the purified Pab.
說明書	Product Datasheet Protocol
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