GPM6A Antibody (C-term)

APR14114G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR14114G		100 μl / ￥5450

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GPM6A Antibody (C-term)

品牌	Leading Biology	貨號(hào)	APR14114G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GPM6A antibody (C-term).
分子量	31210 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein. Cell projection, axon. Cell projection, dendritic spine Cell projection, filopodium. Note=Localizes to cholesterol-rich lipid rafts of the plasma membrane of hippocampal neurons. Localized to plasma membrane of cell bodies and neurites of hippocampal neurons. Localized in membrane protrusions (filopodia and spines) of primary hippocampal neurons. Localized to the growth cone edge membrane of elongating axons (By similarity).
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	232-259 aa
靶點(diǎn)	This GPM6A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 232-259 amino acids from the C-terminal region of human GPM6A.
亞型	Rabbit Ig
通用名	M6A
基因ID	2823
UniProt ID	P51674
功能	Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca(2+) influx. May be involved in regulation of endocytosis and intracellular trafficking of G- protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, FC, E
稀釋方法	WB~~1:1000 FC~~1:10~50
別名	Neuronal membrane glycoprotein M6-a, M6a, GPM6A, M6A
圖像	GPM6A Antibody (C-term) (Cat. APR14114G) western blot analysis in SH-SY5Y cell line lysates (35ug/lane).This demonstrates the GPM6A antibody detected the GPM6A protein (arrow). GPM6A Antibody (C-term) (Cat. APR14114G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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