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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > HRIHFB2025 Antibody (C-term)

HRIHFB2025 Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
AMM08592G 100 μl / ¥5450

HRIHFB2025 Antibody (C-term)

品牌

Leading Biology

貨號

AMM08592G

產(chǎn)品分類

Polyclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality HRIHFB2025 antibody (C-term).

分子量

14470 Da

細胞定位

Antigen Cellular Localization: Nucleus speckle. Golgi apparatus, trans- Golgi network. Note=Nuclear, in a punctate manner. Also found in the trans-Golgi

宿主

Rabbit

種屬反應性

Human

免疫原

98-126 aa

靶點

This HRIHFB2025 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the C-terminal region of human HRIHFB2025.

亞型

Rabbit Ig

通用名

ARB1, C22orf2, CBY, PGEA1

基因ID

UniProt ID

功能

Inhibits the Wnt/Wingless pathway by binding to beta- catenin and inhibiting beta-catenin-mediated transcriptional activation through competition with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin-2/PKD2 and possibly of other intracellular proteins. Promotes adipocyte and cardiomyocyte differentiation.

總結

Inhibits the Wnt/Wingless pathway by binding to beta catenin and inhibiting beta catenin mediated transcriptional activation by competing with TCF/LEF transcription factors. Has also been shown to play a role in regulating the intracellular trafficking of polycystin 2/PKD2 and possibly of other intracellular proteins.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, IHC-P, FC, E

稀釋方法

WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50

別名

Protein chibby homolog 1, ARPP-binding protein, Cytosolic leucine-rich protein, PIGEA-14, PKD2 interactor, Golgi and endoplasmic reticulum-associated 1, CBY1, ARB1, C22orf2, CBY, PGEA1

圖像

Western blot analysis of HRIHFB2025 Antibody (C-term) (Cat. AMM08592G) in MDA-MB231 cell line lysates (35ug/lane). HRIHFB2025 (arrow) was detected using the purified Pab.

Formalin-fixed and paraffin-embedded human brain tissue reacted with HRIHFB2025 Antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.

HRIHFB2025 Antibody (C-term) (Cat. AMM08592G) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.

說明書

數(shù)量

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