PON3 Antibody (N-term)

APR10907G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR10907G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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PON3 Antibody (N-term)

品牌	Leading Biology	貨號	APR10907G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PON3 antibody (N-term).
分子量	39607 Da
細胞定位	Antigen Cellular Localization: Secreted, extracellular space.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	10-38 aa
靶點	This PON3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-38 amino acids from the N-terminal region of human PON3.
亞型	Rabbit Ig
基因ID	5446
UniProt ID	Q15166
功能	Has low activity towards the organophosphate paraxon and aromatic carboxylic acid esters. Rapidly hydrolyzes lactones such as statin prodrugs (e.g. lovastatin). Hydrolyzes aromatic lactones and 5- or 6-member ring lactones with aliphatic substituents but not simple lactones or those with polar substituents.
總結(jié)	PON3 is secreted into the bloodstream and associates with high-density lipoprotein (HDL). The protein also rapidly hydrolyzes lactones and can inhibit the oxidation of low-density lipoprotein (LDL), a function that is believed to slow the initiation and progression of atherosclerosis.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Serum paraoxonase/lactonase 3, PON3
圖像	Western blot analysis of PON3 Antibody (N-term) (Cat. APR10907G) in HepG2 cell line lysates (35ug/lane). PON3 (arrow) was detected using the purified Pab. Formalin-fixed and paraffin-embedded human hepatocarcinoma with PON3 Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. Flow cytometric analysis of HepG2 cells using PON3 Antibody (N-term)(bottom histogram) compared to a negative control cell (top histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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