GIPR Antibody (N-term)

APR14080G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR14080G		100 μl / ￥5450

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GIPR Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR14080G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GIPR antibody (N-term).
分子量	53157 Da
細(xì)胞定位	Antigen Cellular Localization: Cell membrane; Multi-pass membrane protein.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	7-38 aa
靶點(diǎn)	This GIPR antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-38 amino acids from the N-terminal region of human GIPR.
亞型	Rabbit Ig
基因ID	2696
UniProt ID	P48546
功能	This is a receptor for GIP. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.
總結(jié)	GIPR also called glucose-dependent insulinotropic polypeptide, is a 42-amino acid polypeptide synthesized by K cells of the duodenum and small intestine. This protein was originally identified as an activity in gut extracts that inhibited gastric acid secretion and gastrin release, but subsequently was demonstrated to stimulate insulin release potently in the presence of elevated glucose. The insulinotropic effect on pancreatic islet beta-cells was then recognized to be the principal physiologic action of GIP. Together with glucagon-like peptide-1, GIP is largely responsible for the secretion of insulin after eating. The protein is involved in several other facets of the anabolic response.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:10~50 FC~~1:10~50
別名	Gastric inhibitory polypeptide receptor, GIP-R, Glucose-dependent insulinotropic polypeptide receptor, GIPR
圖像	Western blot analysis of GIPR antibody (N-term) (Cat. APR14080G) in HL60 cell line lysates (35ug/lane). GIPR (arrow) was detected using the purified Pab. GIPR Antibody (N-term) (Cat. AP7495A)immunohistochemistry analysis in formalin fixed and paraffin embedded human pancreas tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of GIPR Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated. GIPR Antibody (Center) (Cat. APR14080G) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說(shuō)明書(shū)	Product Datasheet Protocol
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