PDK3 Antibody (N-term)

APR10823G Product Datasheet Protocol

貨號(hào)	貨期	規(guī)格 / 價(jià)格	詢(xún)價(jià)
APR10823G		100 μl / ￥5450

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PDK3 Antibody (N-term)

品牌	Leading Biology	貨號(hào)	APR10823G
產(chǎn)品分類(lèi)	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality PDK3 antibody (N-term).
分子量	46939 Da
細(xì)胞定位	Antigen Cellular Localization: Mitochondrion matrix.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	1-30 aa
靶點(diǎn)	This PDK3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human PDK3.
亞型	Rabbit Ig
通用名	PDHK3
基因ID	5165
UniProt ID	Q15120
功能	Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species.
總結(jié)	PDK3 inhibits the mitochondrial pyruvate dehydrogenase complex by phosphorylation of the E1 alpha subunit, thus contributing to the regulation of glucose metabolism.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, E
稀釋方法	WB~~1:1000
別名	[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial, Pyruvate dehydrogenase kinase isoform 3, PDK3, PDHK3
圖像	Western blot analysis of PDK3 (arrow) using rabbit polyclonal PDK3 Antibody (N-term) ( APR10823G). 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the PDK3 gene (Lane 2) (Origene Technologies). PDK3 Antibody (M1) (Cat. APR10823G) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the PDK3 antibody detected the PDK3 protein (arrow).
說(shuō)明書(shū)	Product Datasheet Protocol
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