DCD Antibody (C-term)

APR10835G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價(jià)格	詢價(jià)
APR10835G		100 μl / ￥5450

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安諾倫（北京）生物科技有限公司

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DCD Antibody (C-term)

品牌	Leading Biology	貨號	APR10835G
產(chǎn)品分類	Polyclonal Antibodies	研究領(lǐng)域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DCD antibody (C-term).
分子量	11284 Da
細(xì)胞定位	Antigen Cellular Localization: Secreted.
宿主	Rabbit
種屬反應(yīng)性	Human
免疫原	74-103 aa
靶點(diǎn)	This DCD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 74-103 amino acids from the C-terminal region of human DCD.
亞型	Rabbit Ig
通用名	AIDD, DSEP
基因ID	117159
UniProt ID	P81605
功能	DCD-1 displays antimicrobial activity thereby limiting skin infection by potential pathogens in the first few hours after bacterial colonization. Highly effective against E.coli, E.faecalis, S.aureus and C.albicans. Optimal pH and salt concentration resemble the conditions in sweat. Also exhibits proteolytic activity.
總結(jié)	DCD is a secreted protein that is subsequently processed into mature peptides of distinct biological activities. The C-terminal peptide is constitutively expressed in sweat and has antibacterial and antifungal activities. The N-terminal peptide, also known as diffusible survival evasion peptide, promotes neural cell survival under conditions of severe oxidative stress. A glycosylated form of the N-terminal peptide may be associated with cachexia (muscle wasting) in cancer patients.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲(chǔ)存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應(yīng)用	WB, IHC-P, FC, E
稀釋方法	WB~~1:1000 IHC-P~~1:50~100 FC~~1:10~50
別名	Dermcidin, 34--, Preproteolysin, Survival-promoting peptide, DCD-1, DCD, AIDD, DSEP
圖像	Western blot analysis of DCD antibody (C-term) (Cat. APR10835G) in T47D cell line lysates (35ug/lane). DCD (arrow) was detected using the purified Pab. DCD Antibody (C-term) (RB18706) IHC analysis in formalin fixed and paraffin embedded human skin tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the DCD Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated. DCD Antibody (C-term) (Cat. APR10835G) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
說明書	Product Datasheet Protocol
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