DSCR1 Antibody (Center)

APR14101G Product Datasheet Protocol

貨號	貨期	規(guī)格 / 價格	詢價
APR14101G		100 μl / ￥5450

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DSCR1 Antibody (Center)

品牌	Leading Biology	貨號	APR14101G
產(chǎn)品分類	Polyclonal Antibodies	研究領域
產(chǎn)品概述	We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality DSCR1 antibody (Center).
分子量	28079 Da
宿主	Rabbit
種屬反應性	Human
免疫原	75-104 aa
靶點	This DSCR1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 75-104 amino acids from the Central region of human DSCR1.
亞型	Rabbit Ig
通用名	ADAPT78, CSP1, DSC1, DSCR1
基因ID	1827
UniProt ID	P53805
功能	Inhibits calcineurin-dependent transcriptional responses by binding to the catalytic domain of calcineurin A. Could play a role during central nervous system development.
總結	DSCR1 (calcipressin 1) interacts with calcineurin A and inhibits calcineurin-dependent signaling pathways, possibly affecting central nervous system development. Thr gene for this protein is located in the minimal candidate region for the Down syndrome phenotype, and is overexpressed in the brain of Down syndrome fetuses. Chronic overexpression of this gene may lead to neurofibrillary tangles such as those associated with Alzheimer disease.
形式	Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
儲存條件	Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
應用	WB, E
稀釋方法	WB~~1:1000
別名	Calcipressin-1, Adapt78, Down syndrome critical region protein 1, Myocyte-enriched calcineurin-interacting protein 1, MCIP1, Regulator of calcineurin 1, RCAN1, ADAPT78, CSP1, DSC1, DSCR1
圖像	The anti-DSCR1 Pab (Cat. APR14101G) is used in Western blot to detect DSCR1 in endothelial cell lysate. Endothelial cell lysate transferred to membrane was incubated with primary antibody at a 1:500 dilution in 2% BSA in TBST at 4 deg C overnight. Data courtesy of Dr. Katherine Healey, NWCRF Institute, School of Biological Sciences, University of Wales Bangor.
說明書	Product Datasheet Protocol
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