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當前位置:首頁 > 抗原抗體、ELISA、WB > 一抗 > Polyclonal Antibodies > GABRB2 Antibody (C-term)

GABRB2 Antibody (C-term)

貨號 貨期 規(guī)格 / 價格 詢價
APR14106G 100 μl / ¥5450

GABRB2 Antibody (C-term)

品牌

Leading Biology

貨號

APR14106G

產(chǎn)品分類

Polyclonal Antibodies

研究領域

產(chǎn)品概述

We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format. We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team. This product is a high quality GABRB2 antibody (C-term).

分子量

59150 Da

細胞定位

Antigen Cellular Localization: Cell junction, synapse, postsynaptic cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein

宿主

Rabbit

種屬反應性

Human

免疫原

346-374 aa

靶點

This GABRB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 346-374 amino acids from the C-terminal region of human GAB_2.

亞型

Rabbit Ig

基因ID

UniProt ID

功能

Component of the heteropentameric receptor for GABA, the major inhibitory neurotransmitter in the vertebrate brain. Functions also as histamine receptor and mediates cellular responses to histamine. Functions as receptor for diazepines and various anesthetics, such as pentobarbital; these are bound at a separate allosteric effector binding site. Functions as ligand- gated chloride channel.

總結

The gamma-aminobutyric acid (GABA) A receptor is amultisubunit chloride channel that mediates the fastest inhibitorysynaptic transmission in the central nervous system. This geneencodes GABA A receptor, beta 2 subunit. It is mapped to chromosome5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2subunits of the GABA A receptor. Alternative splicing of this genegenerates 2 transcript variants, differing by a 114 bp insertion.

形式

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

儲存條件

Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

應用

WB, E

稀釋方法

WB~~1:1000

別名

Gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, GABRB2

圖像

Anti-GABRB2 Antibody (C-term) at 1:500 dilution + HepG2 whole cell lysate Lysates/proteins at 20 μg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size : 59 kDa Blocking/Dilution buffer: 5% NFDM/TBST.

GABRB2 Antibody (C-term) (Cat. APR14106G) western blot analysis in A549 cell line lysates (35ug/lane).This demonstrates the GABRB2 antibody detected the GABRB2 protein (arrow).

說明書

數(shù)量

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