品牌 |
Leading Biology | 貨號 |
APR11248G |
產品分類 |
Polyclonal Antibodies | 研究領域 |
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產品概述 |
We constantly strive to ensure we provide our customers with the best antibodies. As a result of this work we offer this antibody in purified format.
We are in the process of updating our datasheets. If you have any questions regarding this update, please feel free to contact our technical support team.
This product is a high quality HERV-FRD antibody (N-term).
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分子量 |
59523 Da
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細胞定位 |
Antigen Cellular Localization:
Virion.
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宿主 |
Rabbit
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種屬反應性 |
Human
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免疫原 |
79-107 aa
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靶點 |
This HERV-FRD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-107 amino acids from the N-terminal region of human HERV-FRD.
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亞型 |
Rabbit Ig
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通用名 |
ERVFRDE1
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基因ID |
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UniProt ID |
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功能 |
This endogenous retroviral envelope protein has retained its original fusogenic properties and participates in trophoblast fusion and the formation of a syncytium during placenta morphogenesis. The interaction with MFSD2A is apparently important for this process (PubMed:18988732).
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總結 |
Human endogenous retroviruses (HERVs) make upapproximately 8% of the human genome. Although most HERVs arenonfunctional, the HERV-W (ERVWE1; MIM 604659) and HERV-FRDenvelope (env) proteins can induce cell-cell fusion when expressedin cells possessing appropriate receptors (Blaise et al., 2003[PubMed 14557543]).
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形式 |
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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儲存條件 |
Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.
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應用 |
WB, E
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稀釋方法 |
WB~~1:1000
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別名 |
Syncytin-2, Endogenous retrovirus group FRD member 1, Envelope polyprotein, HERV-FRD, HERV-FRD_6p241 provirus ancestral Env polyprotein, Surface protein, SU, Transmembrane protein, TM, ERVFRD-1, ERVFRDE1
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圖像 |
HERV-FRD Antibody (N-term) (Cat. APR11248G) western blot analysis in NCI-H460 cell line lysates (35ug/lane).This demonstrates the HERV-FRD antibody detected the HERV-FRD protein (arrow). |
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說明書 |
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數量 |
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